Application Cases

Experiment Name: Microfluidic Ultrasonic Cavitation Experiment

Research Direction: Microfluidic Ultrasonic Cavitation

Experimental Equipment: ATA-2021B High-Voltage Amplifier, ATA-1220E Broadband Amplifier, Signal Generator, Ultrasonic Transducer, High-Speed Camera, Hydrophone, Oscilloscope, etc.

Experimental Objective:
This experiment utilizes an ultrasonic transducer to drive a microfluidic substrate, generating vibrations in the frequency range of 100 kHz to 2 MHz. These vibrations induce intense acoustic pressure variations within the microchannels. Meanwhile, high-speed microscopic imaging is employed to observe cavitation behavior within the microfluidic system.

Experimental Procedure:
PDMS microchannels were fabricated using soft lithography. The applied voltage was amplified by Aigtek power amplifiers (ATA-1220E/ATA-2021B) to drive the piezoelectric ultrasonic transducer, generating high-frequency mechanical vibrations that induced acoustic pressure variations inside the microchannels. During ultrasonic loading, high-speed microscopic imaging was used to observe cavitation phenomena within the microchannels.

Experimental Results:
It was observed that no cavitation occurred within the microfluidic system at frequencies above 200 kHz. Under ultrasonic loading in the range of 100 kHz–160 kHz, cavitation phenomena were observed in the microchannels, accompanied by wall-attached bubble oscillation instability, microbubble release, and gas nucleus transfer.

Specifications of the ATA-2021B High-Voltage Amplifier Used in the Experiment: